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English name : Ginger
Sanskrit name:
Aardrak
Family : Zingiberaceae
Part used : Rhizome
Extraction
method: |
CO2
extracts | Fortified extracts
Solvent extracts | Whole herb extracts |
More
info |
Traditional
uses: It is used for abdominal pain, anorexia,
arthritis, atonic dyspepsia, bleeding, cancer, chest
congestion, chicken pox, cholera, chronic bronchitis,
cold extremities, colic, colitis, common cold, cough,
cystic fibrosis, diarrhoea, difficulty in breathing,
dropsy, fever, flatulence, indigestion, disorders of
gallbladder, hyperacidity, hypercholesterolemia, hyperglycemia,
indigestion, morning sickness, nausea, rheumatism, sore
throat, throat ache, stomach ache and vomiting. Ginger
forms an important constituent of many Ayurvedic formulations.
Phytochemistry:
The major nonvolatile pungent principles of Zingiber
officinale are a series of phenolic compounds with side
chains of varying length collectively known as “gingerols”.
Among the gingerols 6-gingerol is major while 8-gingerol,
10-gingerol and their corresponding anhydro derivatives
known as “shogaols” are minor constituents.
Other pungent principles of the rhizomes are paradols,
gingerdiols, gingerdiacetates, gingerdiones, 6-gingersulfonic
acid, gingerenones etc. The rhizome also contains volatile
oil with sesquiterpene hydrocarbons viz. a-zingiberene,
ß-sesquiphellandrene and ar-curcumene as major
constituents; diterpenes and gingerglycolipids A, B
and C.
Pharmacology:
Zingiber officinale has been evaluated for various pharmacological
activities. Zingiber officinale is found to have, anti-nausea,
anti-emetic and anti-ulcer properties. Zingiber officinale
is been reported to have, anti-inflammatory, anti-arthritic
activity. In addition it is reported to have hepatoprotective,
hypoglycemic, hypolipidemic and cardiotonic effect.
Marker constituents: Volatile
oils, gingerols, shogaols.
Main use: Digestive acid,
anti-emetic, anti-inflammatory. Specification:
20% Gingerols
| SL NO |
TESTS |
LIMITS |
PROTOCOL |
| 1. |
Description
|
Brown liquid with characteristic odour. |
| 2. |
Physico-chemical analysis
|
|
|
| Moisture (%w/w) |
< 5.0 |
As per USP <921> Method II |
| Ash content (%w/w) |
< 3.5 |
As per USP<561>
Vegetable Drugs |
| Acid insoluble Ash (%w/w) |
< 1.0 |
| Volatile oil (%w/v) |
> 8.0 |
As per USP<791> |
| 3. |
Heavy metal analysis |
|
|
| Lead |
< 10 ppm |
AAS / ICP –ES |
| Cadmium |
< 1 ppm |
| Arsenic |
< 2 ppm |
| 4. |
Microbiological analysis |
|
As per WHO/PHARMA/92.559/Rev.1 Pg.49-52 |
| As per FIP Guidelines |
< 104 cfu g-1 |
| Total Enterobacteriaceae |
< 102 org g-1 |
| Total Fungal Count |
< 102 fs g-1 |
| 5. |
Test for Specific Pathogen |
|
| As per FIP Guidelines |
|
| E.coli (1g) |
Absent |
| Salmonella Sp. (10g) |
Absent |
| S.aureus (1g) |
Absent |
| 6. |
Mycotoxin analysis |
< 5ppb |
As per USP Test for Aflatoxins |
| Aflatoxins (B1 + B2 + G1 + G2) |
| 7. |
Pesticide residue analysis |
To comply with
USP |
As per AOAC / USP |
| As per USP & BP Limits |
| Organochlorine Pesticides |
| Organophosphorus Pesticides |
| Synthetic pyrethroids |
| 8. |
Phytochemical analysis |
> 20.0 |
By HPLC |
| Total Gingerols (%w/w) |
Note:
1. Zingiber officinale extract is also available with
> 5%w/w total Gingerols in powder form.
2. Residual pesticide analysis is performed only on request.
Specification: 5% Gingerols
| SL NO |
TESTS |
LIMITS |
PROTOCOL |
| 1. |
Description
|
Brown liquid with characteristic odour. |
| 2. |
Physico-chemical analysis
|
|
|
| Moisture (%w/w) |
< 5.0 |
As per USP <921> Method II |
| 3. |
Particle Size |
|
|
| Bulk Density (%g/cc) |
0.20 – 0.80 |
As per USP <616> 1913-1914 Method
– I |
| Tapped bulk density |
0.25 – 0.90 |
| Material passing through 30# BS/35 ASTM (%w/w) |
99.0 |
As per USP <786> Particle Size distribution. |
| 4. |
Heavy metal analysis |
|
AAS / ICP –ES |
| Lead |
< 10 ppm |
| Cadmium |
< 1 ppm |
| Arsenic |
< 2 ppm |
| 5. |
Microbiological analysis |
|
|
| As per FIP Guidelines |
|
|
| Total Viable Aerobic Count |
< 104 cfu g-1 |
|
| Total Enterobacteriaceae |
< 102 org g-1 |
|
| Total Fungal Count |
< 102 fs g-1 |
|
| 6. |
Test for Specific Pathogen |
|
As per WHO/PHARMA/92.559/Rev.1 Pg.49-52 |
| As per FIP Guidelines |
Absent |
| E.coli (1g) |
| Salmonella Sp. (10g) |
| S.aureus (1g) |
| 7. |
Mycotoxin analysis |
< 5ppb |
As per USP Test for Aflatoxins |
| Aflatoxins (B1 + B2 + G1 + G2) |
| 8. |
Pesticide residue analysis |
To comply with
USP |
As per AOAC / USP |
| As per USP & BP Limits |
| Organochlorine Pesticides |
| Organophosphorus Pesticides |
| Synthetic pyrethroids |
| 9. |
Phytochemical analysis |
5.0 |
By HPLC |
| Total Gingerols (%w/w) |
|